OncoMetric Hub – 50-Question Quick-Reference FAQ

A cloud platform that hosts precision-oncology calculators for biomarker matching, neoantigen vaccine planning, and immunotherapy cost analysis.

Molecular pathologists, medical oncologists, translational researchers, tumor-board coordinators, and hospital finance teams.

No—current calculators are pancreas-optimized, but the framework can ingest any solid-tumor data set.

A free “Research” tier allows limited runs; paid Clinical Pro and Enterprise plans add EMR integration, APIs, and support.

No. All tools run in any modern browser (Chrome, Edge, Firefox, Safari).

Click Sign Up, verify your email, and choose Research (free) or a paid tier.

Yes—SAML 2.0, Okta, Azure AD, and institutional Shibboleth.

Yes. Paid plans include team workspaces with role-based permissions.

TLS 1.3, short-lived JWT tokens, and automatic logout after 30 minutes of inactivity.

Every calculation and file action is audit-logged for 10 years (HIPAA/21 CFR Part 11).

Any combination of MMR gene mutations, IHC status, PCR MSI result, and tumor-mutational-burden value.

Yes—VCF parsing auto-detects MLH1, MSH2, MSH6, and PMS2 variants.

Weighted points for gene hits, IHC loss, PCR result, and TMB (capped at 20); normalized to 0–100.

A score ≥ 70 triggers the green “Excellent candidate for PD-1 therapy” tag.

Yes—logic mirrors NCCN v1.2025 GI and pancreas guidelines plus FDA tumor-agnostic approvals.

JSON array with peptide, IC50 (nM), expression, and clonal boolean fields.

Not yet—planned for Q4 2025.

Affinity <50 nM, high transcript expression, clonal status, and CD8 density contribute up to 100 points.

HLA-A/B/C binding context is auto-identified if provided; otherwise default population alleles are assumed.

Enterprise API or CSV bulk uploader supports cohort analyses.

USD, EUR, GBP, CNY; custom currency multipliers allowed.

Default values by disease stage and biomarker but editable; integration with ImmunoMatch can pre-fill.

Bundled-care (percentage), outcome-based refunds, and formulary price concessions.

Yes—one click to PDF or CSV for health-economics reports.

Roadmap item—patient-reported outcomes module coming 2026.

REST/JSON beta endpoints for score computation and cohort upload; GraphQL planned.

FHIR R4 write-back module with Epic App Orchard and Cerner Ignite Gallery apps.

Calculators’ UI is MIT-licensed; core algorithms are closed but published in peer-review papers.

Chrome ≥ v108, Edge ≥ 108, Firefox ≥ 102, Safari ≥ 15.

Responsive design works on tablets; phone UI is view-only for now.

Only if the user uploads it; data are encrypted at rest, region-locked, and deletable on-demand.

Yes—signed BAA available for paid plans.

“Right-to-be-forgotten” button purges user data within 24 hours.

AWS Region-US East (Ohio) and EU-West (Ireland) with fail-over clusters.

SOC-2 Type II and ISO 27001 certifications renewed annually.

Monthly CI/CD pushes synced to latest PubMed and NCCN releases.

Yes—anonymized benchmarking cohorts are shared on GitHub under CC-BY-4.0.

Enterprise users can opt in to a federated-learning pool; data never leave your firewall.

Used in two ASCO 2025 posters and a forthcoming JCO Precision Oncology article.

Medical-affairs board with GI oncologists reviews every guideline change before production.

In-app chat, Slack community, and 24/7 email ticketing for Pro tiers.

Free 60-minute Zoom session plus CME-accredited video modules.

Docs hub with quick-start guides, Swagger API refs, and methodology PDFs.

Use the “Feature Request” button; roadmap voting determines priority.

Benchling and LabKey plugins in beta; CSV bridge available now.

Credit card, ACH, purchase order; annual invoicing for enterprises.

Yes—90-day no-cost pilot for NCI-Designated Cancer Centers.

40 % off Clinical Pro for institutions with <500 new cancer cases/year.

Month-to-month; prorated refunds for annual plans within 30 days of notice.

Enterprise license allows custom domain, logo, and color scheme for CROs or pharma sponsors.